NCCR "RNA&Disease"
Our Group is part of the external page national NCCR initiative “RNA and Disease”.
As part of the network, we operate an RNA synthesis platform to help collaborators access complex RNA structures. See the news releases and the new papers concerning collaborations of our Platform team with the Polacek group in Bern (external page news release, external page pubmed) and the Jinek group at the University of Zurich (external page news release, external page pubmed). Our collaborations include projects related to:
- The role of Muscleblind (MBNL1) in miRNA biogenesis and its effects on myotonic dystrophy and cardiac dysfunction
- Splicing correction of the ferrochelatase gene for treatment of erythropoietic protoporphyria (EPP)
- Non-canonical mechanisms of miRNA – mRNA regulation.